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Literature summary extracted from

  • Popovic, T.; Brzin, J.; Kos, J.; Lenarcic, B.; Machleidt, W.; Ritonja, A.; Hanada, K.; Turk, V.
    A new purification procedure of human kidney cathepsin H, its properties ans kinetic data (1988), Biol. Chem. Hoppe-Seyler, 369, 175-183.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.22.16 chicken cystatin Ki: 0.1 nM Homo sapiens
3.4.22.16 Human cystatin C Ki: 0.01-0.03 nM Homo sapiens
3.4.22.16 human stefin A Ki: 0.1-0.16 nM Homo sapiens
3.4.22.16 human stefin B Ki: 0.003 nM Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.22.16 24000
-
 1 * 24000, 1 * 4000, SDS-PAGE, partial Homo sapiens
3.4.22.16 28000
-
 gel filtration Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.22.16 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.22.16
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.22.16 kidney
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.22.16 additional information
-
 40% inactive enzyme in vivo Homo sapiens

Storage Stability

EC Number Storage Stability Organism
3.4.22.16 -20°C, 0.02 M sodium acetate buffer, pH 5.2, 1 mM EDTA, several months without loss of activity Homo sapiens

Subunits

EC Number Subunits Comment Organism
3.4.22.16 dimer 1 * 24000, 1 * 4000, SDS-PAGE, partial Homo sapiens
3.4.22.16 monomer 1 * 28000, SDS-PAGE, partial Homo sapiens
3.4.22.16 More amino acid analysis Homo sapiens